Musical practice and BDNF plasma levels as a potential marker of synaptic plasticity: an instrument of rehabilitative processes.
Identifieur interne : 000214 ( Main/Exploration ); précédent : 000213; suivant : 000215Musical practice and BDNF plasma levels as a potential marker of synaptic plasticity: an instrument of rehabilitative processes.
Auteurs : Alessandro Minutillo [Italie] ; Gabriele Panza [Italie] ; Massimo Carlo Mauri [Italie]Source :
- Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [ 1590-3478 ] ; 2020.
Abstract
BACKGROUND AND OBJECTIVES
The aim of the study was to investigate the influence of musical practice on brain plasticity. BDNF (brain-derived neurotrophic factor) is a neurotrophin involved in neuroplasticity and synaptic function.
MATERIALS AND METHODS
We recruited 48 healthy subjects of equal age and sex (21 musicians and 27 non-musicians). All subjects were administered the AQ (Autism-Spectrum Questionnaire) and plasma levels (PLs) of BDNF, oxytocin (OT), and vasopressin (VP) were measured in the blood sample of every participant.
RESULTS
The difference between BDNF PLs in the two groups was found to be statistically significant (t = - 2.214, p = 0.03). Furthermore, oxytocin (OT) PLs and musical practice were found to be independent positive predictors of BDNF PLs (p < 0.04). We also found a negative correlation between BDNF PLs and AD (attention to detail) sub-scale score of AQ throughout the whole sample. Assuming BDNF PLs to be a marker of synaptic plasticity, higher PLs could be associated with the activation of alternative neural pathways: a lower score in the "attention to detail" sub-scale could imply greater flexibility of higher cerebral functions among musicians. Further researches should be conducted to assess the rehabilitative usefulness of these findings among patients affected by psychiatric disorders.
DOI: 10.1007/s10072-020-04715-9
PubMed: 32940801
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Musical practice and BDNF plasma levels as a potential marker of synaptic plasticity: an instrument of rehabilitative processes.</title><author><name sortKey="Minutillo, Alessandro" sort="Minutillo, Alessandro" uniqKey="Minutillo A" first="Alessandro" last="Minutillo">Alessandro Minutillo</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. alessandro.minutillo@unimi.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy. alessandro.minutillo@unimi.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Pathophysiology and Transplantation, University of Milan, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Panza, Gabriele" sort="Panza, Gabriele" uniqKey="Panza G" first="Gabriele" last="Panza">Gabriele Panza</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Mauri, Massimo Carlo" sort="Mauri, Massimo Carlo" uniqKey="Mauri M" first="Massimo Carlo" last="Mauri">Massimo Carlo Mauri</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32940801</idno><idno type="pmid">32940801</idno><idno type="doi">10.1007/s10072-020-04715-9</idno><idno type="wicri:Area/Main/Corpus">000159</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000159</idno><idno type="wicri:Area/Main/Curation">000159</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000159</idno><idno type="wicri:Area/Main/Exploration">000159</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Musical practice and BDNF plasma levels as a potential marker of synaptic plasticity: an instrument of rehabilitative processes.</title><author><name sortKey="Minutillo, Alessandro" sort="Minutillo, Alessandro" uniqKey="Minutillo A" first="Alessandro" last="Minutillo">Alessandro Minutillo</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. alessandro.minutillo@unimi.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy. alessandro.minutillo@unimi.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Pathophysiology and Transplantation, University of Milan, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Panza, Gabriele" sort="Panza, Gabriele" uniqKey="Panza G" first="Gabriele" last="Panza">Gabriele Panza</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Mauri, Massimo Carlo" sort="Mauri, Massimo Carlo" uniqKey="Mauri M" first="Massimo Carlo" last="Mauri">Massimo Carlo Mauri</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author></analytic><series><title level="j">Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology</title><idno type="eISSN">1590-3478</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND AND OBJECTIVES</b></p><p>The aim of the study was to investigate the influence of musical practice on brain plasticity. BDNF (brain-derived neurotrophic factor) is a neurotrophin involved in neuroplasticity and synaptic function.</p></div><div type="abstract" xml:lang="en"><p><b>MATERIALS AND METHODS</b></p><p>We recruited 48 healthy subjects of equal age and sex (21 musicians and 27 non-musicians). All subjects were administered the AQ (Autism-Spectrum Questionnaire) and plasma levels (PLs) of BDNF, oxytocin (OT), and vasopressin (VP) were measured in the blood sample of every participant.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>The difference between BDNF PLs in the two groups was found to be statistically significant (t = - 2.214, p = 0.03). Furthermore, oxytocin (OT) PLs and musical practice were found to be independent positive predictors of BDNF PLs (p < 0.04). We also found a negative correlation between BDNF PLs and AD (attention to detail) sub-scale score of AQ throughout the whole sample. Assuming BDNF PLs to be a marker of synaptic plasticity, higher PLs could be associated with the activation of alternative neural pathways: a lower score in the "attention to detail" sub-scale could imply greater flexibility of higher cerebral functions among musicians. Further researches should be conducted to assess the rehabilitative usefulness of these findings among patients affected by psychiatric disorders.</p></div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">32940801</PMID><DateRevised><Year>2020</Year><Month>09</Month><Day>17</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1590-3478</ISSN><JournalIssue CitedMedium="Internet"><PubDate><Year>2020</Year><Month>Sep</Month><Day>17</Day></PubDate></JournalIssue><Title>Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology</Title><ISOAbbreviation>Neurol Sci</ISOAbbreviation></Journal><ArticleTitle>Musical practice and BDNF plasma levels as a potential marker of synaptic plasticity: an instrument of rehabilitative processes.</ArticleTitle><ELocationID EIdType="doi" ValidYN="Y">10.1007/s10072-020-04715-9</ELocationID><Abstract><AbstractText Label="BACKGROUND AND OBJECTIVES" NlmCategory="OBJECTIVE">The aim of the study was to investigate the influence of musical practice on brain plasticity. BDNF (brain-derived neurotrophic factor) is a neurotrophin involved in neuroplasticity and synaptic function.</AbstractText><AbstractText Label="MATERIALS AND METHODS" NlmCategory="METHODS">We recruited 48 healthy subjects of equal age and sex (21 musicians and 27 non-musicians). All subjects were administered the AQ (Autism-Spectrum Questionnaire) and plasma levels (PLs) of BDNF, oxytocin (OT), and vasopressin (VP) were measured in the blood sample of every participant.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">The difference between BDNF PLs in the two groups was found to be statistically significant (t = - 2.214, p = 0.03). Furthermore, oxytocin (OT) PLs and musical practice were found to be independent positive predictors of BDNF PLs (p < 0.04). We also found a negative correlation between BDNF PLs and AD (attention to detail) sub-scale score of AQ throughout the whole sample. Assuming BDNF PLs to be a marker of synaptic plasticity, higher PLs could be associated with the activation of alternative neural pathways: a lower score in the "attention to detail" sub-scale could imply greater flexibility of higher cerebral functions among musicians. Further researches should be conducted to assess the rehabilitative usefulness of these findings among patients affected by psychiatric disorders.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Minutillo</LastName><ForeName>Alessandro</ForeName><Initials>A</Initials><Identifier Source="ORCID">https://orcid.org/0000-0002-8974-289X</Identifier><AffiliationInfo><Affiliation>Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. alessandro.minutillo@unimi.it.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy. alessandro.minutillo@unimi.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Panza</LastName><ForeName>Gabriele</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mauri</LastName><ForeName>Massimo Carlo</ForeName><Initials>MC</Initials><AffiliationInfo><Affiliation>Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>09</Month><Day>17</Day></ArticleDate></Article><MedlineJournalInfo><Country>Italy</Country><MedlineTA>Neurol Sci</MedlineTA><NlmUniqueID>100959175</NlmUniqueID><ISSNLinking>1590-1874</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">BDNF</Keyword><Keyword MajorTopicYN="N">Biological neurosciences</Keyword><Keyword MajorTopicYN="N">Music</Keyword><Keyword MajorTopicYN="N">Psychiatric rehabilitation</Keyword><Keyword MajorTopicYN="N">Synaptic plasticity</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>05</Month><Day>07</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>09</Month><Day>08</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>9</Month><Day>17</Day><Hour>12</Hour><Minute>17</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>9</Month><Day>18</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>9</Month><Day>18</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32940801</ArticleId><ArticleId IdType="doi">10.1007/s10072-020-04715-9</ArticleId><ArticleId IdType="pii">10.1007/s10072-020-04715-9</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Italie</li></country><region><li>Lombardie</li></region><settlement><li>Milan</li></settlement></list><tree><country name="Italie"><region name="Lombardie"><name sortKey="Minutillo, Alessandro" sort="Minutillo, Alessandro" uniqKey="Minutillo A" first="Alessandro" last="Minutillo">Alessandro Minutillo</name></region><name sortKey="Mauri, Massimo Carlo" sort="Mauri, Massimo Carlo" uniqKey="Mauri M" first="Massimo Carlo" last="Mauri">Massimo Carlo Mauri</name><name sortKey="Minutillo, Alessandro" sort="Minutillo, Alessandro" uniqKey="Minutillo A" first="Alessandro" last="Minutillo">Alessandro Minutillo</name><name sortKey="Panza, Gabriele" sort="Panza, Gabriele" uniqKey="Panza G" first="Gabriele" last="Panza">Gabriele Panza</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SanteMusiqueV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000214 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000214 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SanteMusiqueV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:32940801
|texte= Musical practice and BDNF plasma levels as a potential marker of synaptic plasticity: an instrument of rehabilitative processes.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:32940801" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a SanteMusiqueV1
| This area was generated with Dilib version V0.6.38. |  |